** 0.01, one-way ANOVA. in Caspr1-depleted HBMECs was recovered by manifestation of exogenous ADAM9. Then, we recognized that Caspr1 specifically regulates the manifestation of ADAM9, but not ADAM10 and ADAM17, at transcriptional level by nuclear factor-B (NF-B) signaling pathway. Caspr1 knockout attenuated the activation of NF-B and prevented the nuclear … Continue reading ** 0